Tshuaj Tshiab Cancer Rau Cov Dev Nrog Qhov Ncauj Melanomas
Tshuaj Tshiab Cancer Rau Cov Dev Nrog Qhov Ncauj Melanomas

Video: Tshuaj Tshiab Cancer Rau Cov Dev Nrog Qhov Ncauj Melanomas

Video: Tshuaj Tshiab Cancer Rau Cov Dev Nrog Qhov Ncauj Melanomas
Video: TSHUAJ NTSUAB ZOO QOG CANCER 2024, Kaum ib hlis
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Peb tau hais ntau yam txog cov tshuaj tiv thaiv qeeb, tab sis tsuas yog hais txog cov tshuaj tiv thaiv uas siv los tiv thaiv kab mob. Cov ntsiab lus niaj hnub no yuav sib txawv me ntsis - tshuaj tiv thaiv uas kho tau tus kab mob preexisting: qhov ncauj tsis huv hauv cov dev.

Cov ncauj lus mob ncauj lus tsis zoo. Vim tias lawv muab zais rau hauv tus dev lub qhov ncauj, lawv yuav tsis pom thiab txheeb xyuas kom txog thaum cov qog loj, tsawg kawg yog txheeb ze rau nws qhov chaw nyob. Melanomas tshwm sim los ntawm cov nqaij mos ntawm lub qhov ncauj (cov pos hniav, tus nplaig, thiab lwm yam) tab sis loj hlob sai thiab tuaj yeem ua rau pob txha pob txha. Qhov ncauj melanomas tseem metastasize sai sai. Ib txoj kev tshawb nrhiav tau pom tias 80% ntawm cov dev uas kuaj pom ntawm qhov ncauj tawm ntawm lub qhov ncauj tau mob qog ua paug hauv lawv cov qog ntshav thiab / lossis ntsws.

Cov yam ntxwv no tau ua rau kev kho lub qhov ncauj tawm ntawm cov dev tsis yooj yim. Hauv qee kis, kev phais mob radical (piv txwv, tshem tawm ntawm ib feem ntawm lub puab tsaig) yog qhov tsim nyog los tswj tus kabmob hauv zos, tab sis tib lub sijhawm muaj feem ntau heev uas cov qog mob cancer tau kis mus rau lwm qhov ntawm lub cev. Kev siv tshuaj kho mob tuaj yeem pab tau, tab sis feem ntau, nws tsis yog txhua yam zoo rau hom mob qog ntshav.

Ob peb xyoos dhau los, canine qhov ncauj melanoma tshuaj tiv thaiv ntaus ua lag luam. Nws hu ua tshuaj tiv thaiv (lossis ntau qhov tsim nyog, tshuaj tiv thaiv kab mob) vim tias nws ua haujlwm los ntawm kev ua kom muaj zog tiv thaiv kab mob tiv thaiv kab mob. Tab sis tsis zoo li tshuaj ib txwm, tshuaj tiv thaiv kev tiv thaiv, nws tau muab rau cov tsiaj uas twb muaj tus kab mob lawm.

Cov tshuaj tiv thaiv muaj cov DNA uas muaj cov gene rau cov lej ntawm tib neeg tyrosinase, uas yog ib hom protein uas tsim nyob rau qhov siab dua ib txwm muaj los ntawm melanoma hlwb. Tom qab tau txhaj tshuaj nrog cov tshuaj tiv thaiv (los ntawm kev siv cov khoom siv hloov chaw), tus dev cov leeg nqaij hauv thaj chaw tau noj cov DNA no thiab tom qab ntawd pib tsim cov tib neeg tyrosinase protein. Raws li daim ntawv qhia tshuaj tiv thaiv: "Tus tib neeg tyrosinase protein txawv txaus los ntawm canine tyrosinase protein uas nws yuav txhawb cov tshuaj tiv thaiv kab mob, tab sis zoo li txaus rau canine tyrosinase tias cov tshuaj tiv thaiv kab mob tau zoo tiv thaiv canine melanoma hlwb uas nthuav qhia tyrosinase."

Cov dev tau pib txhaj tshuaj txhua ob lub lis piam rau tag nrho plaub koob thiab tom qab ntawd yuav tsum tau txhaj tshuaj ntxiv rau txhua rau lub hlis. Nws yuav tsum raug sau tseg tias cov tshuaj tiv thaiv tau sau npe rau kev siv tom qab tus kab mob hauv zos tau tswj hwm qhov loj tshaj plaws (los ntawm kev phais mob thiab / lossis hluav taws xob) thiab metastasis tsis muaj pov thawj lossis tau muaj kev tiv thaiv (piv txwv, cov qog cuam tshuam tau raug tshem tawm phais) Cov. Cov kws kho tsiaj tau sim cov tshuaj tiv thaiv thaum cov tsis tau ua tiav thiab qee cov lus tshaj tawm tau hais txog qhov zoo, tab sis cov tswv yuav tsum tsis cia siab tias qhov tshuaj tiv thaiv yuav pom zoo lossis tshwj xeeb tshaj yog nyob hauv cov xwm txheej no.

Cov khoom no yog qhov tshiab heev uas muab rau tus tswv lub tswv yim dab tsi los xav kom txog kev txhim kho hauv lub sijhawm muaj sia nyob yog qhov nyuaj. Nws tau tshaj tawm raws li USDA Veterinary Biological Product License, uas txhais tau tias USDA ntseeg tau tias nws muaj kev nyab xeeb thiab muaj qhov "xav tias yuav ua tau ntawm kev ua tau zoo raws li kev sim ua ntej." Cov tuam txhab tsim tshuaj tiv thaiv tau tshaj tawm tias "Lub sijhawm no daim ntawv tso cai tsis pub dhau, yuav tshawb nrhiav ntxiv los txhawb kev nyab xeeb thiab kev ua tau zoo ntawm cov tshuaj tiv thaiv." Txog tam sim no, cov kev tshawb fawb tau qhia qee qhov sib xyaw ua ke. Kws kho tsiaj oncologist qhia txog ntau zaj dab neeg ua tau zoo (dev nyob ntev dua li tau xav) thiab cov dev uas tuag ua ntej lawv muaj mob muaj feem yuav zoo dua vim qhov tshuaj tiv thaiv.

Nrog rau lub sijhawm, txoj kev xaiv kev kho mob tshiab no yuav ua pov thawj los ua qhov tseem ceeb ua ntej hauv kev kho mob ntawm qhov ncauj ntawm qhov ncauj hauv cov dev thiab muaj txoj hauv kev rau cov kev kho mob zoo sib xws hauv tib neeg.

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Dr. Jennifer Coates

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