SCID - Nees - Kev Tiv Thaiv Kab Mob Ua Txhuv Ntau Yam

2024 Tus sau: Daisy Haig | [email protected]. Kawg hloov kho: 2023-12-17 03:09

SCID hauv Foals

Kev txhaj tshuaj tiv thaiv kab mob tsis haum (SCID) yog ib qho autosomal (tsis txuas nrog lub chromosomes rau kev sib deev) kev mob tshwm sim hauv lub cev muaj feem cuam tshuam rau Arabian foals. Cov kab mob no tsis tuaj yeem tsim cov tshuaj B thiab T lymphocytes, uas yog cov qe ntshav tshwj xeeb uas tseem ceeb rau kev tiv thaiv kab mob. Yog tias tsis muaj B thiab T lymphocytes, lub cev tiv thaiv kab mob tsis tuaj yeem tawm tsam antigens tau zoo.

SCID-cuam tshuam cov zaub mov zoo li qub thaum yug, tab sis tom qab thawj ob peb lub hlis ntawm lub neej, lawv pib raug mob los ntawm ntau yam kab mob. Lub sijhawm lub sijhawm no suav nrog kev poob ntawm cov niam tiv thaiv kab mob uas lawv tau noj los ntawm lawv niam cov kua mis thaum yug.

Ib qho kev mob tshwm sim tshaj plaws ntawm kev kis tus kab mob hauv SCID cov ntsaum yog adenovirus, uas ua rau mob ntsws ntau heev. Lwm hom kev sib kis mob tuaj yeem koom nrog cov kab mob, fungal, thiab protozoal. Tam sim no kuaj cov SCID caj ces muaj kev lag luam.

Cov tsos mob thiab Hom

Cov tsos mob yuav sib txawv raws li hom kev kis mob ntawm tus foal succumbs rau, suav nrog:

• Tshuaj mob ntsws: qhov ntswg tawm, hnoos, ua tsis taus pa (ua pa)
• Zawv plab
• Ua npaws
• Lub cev yuag
• Stunted kev loj hlob
• Pheej pheej qog cov lymphocytes ntawm cov ntshav ua haujlwm

Ua rau

Qhov kev hloov caj ces no ua rau ib qhov kev tshem cov gene uas tiv thaiv kev tsim cov enzyme uas tsim nyog rau kev loj hlob ntawm B thiab T lymphocytes (ib hom qe ntshav dawb), uas xav tau los tua tawm kis mob.

Kev kuaj mob

Hauv lub sijhawm dhau los, kev ntsuas tau ua tiav los ntawm kev soj ntsuam cov kab mob hauv tsev kho mob thiab kuaj xyuas cov ntshav tiav ua tiav rau kev pheej hmoo ntawm lymphocytes. Txhawm rau pab txhawb nqa kev kuaj mob, kuaj ntshav-ua lub cev tiv thaiv kab mob siab dawb tau ua tiav. Yog tias nws pom tias tsis muaj cov ntshiab IgM (ib hom ntawm cov tshuaj tiv thaiv) hauv kev tiv thaiv ntshav, tom qab ntawv foal tau kuaj pom nrog SCID.

Tam sim no, kev kuaj txog caj ces rau SCID tau muaj. Qhov kev kuaj pom no yuav tsum kuaj ib qho ntshav ntawm tag nrho los yog sab plhu thiab yog nyob ntawm polymerase saw cov kev sib tw (PCR) cov txuj ci kom nthuav dav foal's DNA tam sim no hauv cov qauv. Qhov kev ntsuam xyuas no tseem tuaj yeem ua kom pom cov xeeb txawm muaj ntawm tus noob kom tus tswv cov tswv cuab tuaj yeem tiv thaiv ob tus neeg nqa khoom los ntawm kev yug tsiaj, uas yuav muaj txoj hauv kev los tsim SCID foal.

Kev Kho Mob

Tsis muaj ib txoj kev kho tau tus mob no. Yog tias koj tuaj yeem kho tus mob foal ntawm ib tus kab mob, txhua tus kab mob ntawm lwm cov kab mob, kab mob, thiab lwm yam kab mob sib kis tau tuaj yeem tseem muaj peev xwm kis tau rau tus kab mob vim tias nws tsis muaj qhov tshuaj tiv thaiv kab mob los tiv thaiv nws. Cuam tshuam foals feem ntau tuag ncig lossis ua ntej tsib lub hlis hnub nyoog. Euthanasia yog kev pom zoo.

Nyob thiab Tswj

Ua ntej yuav nteg qe koj cov av ntawm Arabian los yog tso cai rau koj tus Arabian stallion los pabcuam mare, nco ntsoov kuaj koj tus nees rau kev txhaj tshuaj tiv thaiv kab mob hnyav thaum nws yog tus neeg nqa khoom. Qhov no yog qhov tseem ceeb tshaj plaws, vim tias tus kab mob no tau ua neeg tuag taus nyob hauv foals.