Chemo Kev Kho Mob Rau Mast Cell Tumors Hauv Cov Tsiaj
Chemo Kev Kho Mob Rau Mast Cell Tumors Hauv Cov Tsiaj

Video: Chemo Kev Kho Mob Rau Mast Cell Tumors Hauv Cov Tsiaj

Video: Chemo Kev Kho Mob Rau Mast Cell Tumors Hauv Cov Tsiaj
Video: Txooj lis qhia txog kev kho mob,yuav kho li cas thiaj kho tau tus mob qhov ncauj zoo 14/10/2020 2024, Kaum ib hlis
Anonim

Muaj ob feem tseem ceeb ntawm kev siv tshuaj rau kev kho mob mast cell qog hauv cov dev: ntau dua qub "tshuaj" kev siv tshuaj kho mob (xws li, CCNU, vinblastine, prednisone), thiab cov chav kawm tshiab ntawm cov tshuaj hu ua tyrosine kinase inhibitors (Palladia thiab Kinavet).

Kev siv tshuaj kho mob ib txwm ua haujlwm los ntawm kev ua rau muaj kev puas tsuaj rau DNA hauv hlwb, tsis hais txog ntawm lub cell puas hlav lossis cov cell zoo. Qhov no yog vim li cas rau qee qhov kev mob tshwm sim pom nrog kev siv tshuaj kho mob, suav nrog kev mob tshwm sim tsis zoo thiab txo qis cov qe ntshav dawb hauv lub cev.

Lub tshuab ntawm kev ua ntawm tyrosine kinase inhibitors (TKIs) sib txawv heev. Cov tshuaj no ua haujlwm feem ntau los ntawm inhibiting qhov kev ua ntawm lub receptor nyob rau saum npoo ntawm mast hlwb uas tau hloov pauv nyob hauv thaj tsam li 20-30 feem pua ntawm cov qog. Thaum cov receptor no sib hloov, nws ua rau kev tswj hwm cov cell tsis sib luag, ua rau muaj qog loj tuaj.

TKI kuj tseem tuaj yeem ua haujlwm los ntawm kev txwv kev loj hlob ntawm cov hlab ntshav mus rau cov qog hlwb (qhov no hu ua anti-angiogenesis kho). Qhov kev sib xyaw ua haujlwm no sib cais los ntawm cov txheej txheem hais txog yav dhau los, txhais tau tias cov qog tsis muaj qhov tshwj xeeb receptor hloov tuaj yeem tseem muaj cov lus teb zoo rau kev kho mob.

TKIs yog cov tshuaj noj hauv lub qhov ncauj txuas ntxiv hauv tsev. Cov dev yuav tsum muaj qhov "lub xeev tus lej" sib luag ntawm cov tshuaj no hauv lawv cov ntshav kom ua kom cov receptor tso tawm tas li. Cov receptor tshwm sim nyob rau lwm lub hlwb hauv lub cev, yog li cov kev mob tshwm sim tuaj yeem tshwm sim nrog TKIs ib yam nkaus, tab sis feem ntau muaj kev txwv hauv lawv cov spectrum.

Cov lus nqa hauv tsev rau canine mast cell hlav yog:

  1. Lawv yog qhov tsis muaj peev xwm xav tau ntawm lawv tus cwj pwm.
  2. Qhov twv loj tshaj plaws ntawm kev coj xeeb ceem yog qeb ntawm qog, uas tuaj yeem txiav txim siab TSO los ntawm kev txiav tawm me me xwb.
  3. Cov kev sim ua ntu zus yog qhov tseem ceeb rau kev saib xyuas kev kis tus kabmob thiab yuav tsum suav nrog kev ua haujlwm, thaj chaw ntawm lub ntsws ua kom lub cev txhawm, txhawm rau lub plab, thiab qee kis, mob pob txha.
  4. Kev phais mob yog qhov tseem ceeb ntawm kev kho rau feem ntau cov dev.
  5. Kev siv hluav taws xob kho thiab kev siv tshuaj kho mob ua si lub luag haujlwm rau cov dev nrog cov mast cell hlav - sab laj nrog kws kho tsiaj oncologist kom ntseeg tau tias koj paub txhua txoj kev xaiv los kho koj tus dev!
image
image

dr. joanne intile

Pom zoo: