5 Txoj Kev Tsis Tsim Nyog Veterinary Science Yuav Pab Tau Peb Cov Tsiaj

2024 Tus sau: Daisy Haig | [email protected]. Kawg hloov kho: 2023-12-17 03:09

_{Duab ntawm iStock.com/skynesher}

Los ntawm Diana Bocco

Veterinary science tau dhau los ntev ntawm kaum xyoo dhau los. Cov tsiaj muaj sia nyob ntev dua, muaj kev noj qab haus huv thiab muaj lub neej ua tsaug ntau dua rau kev tshawb fawb xws li kev hloov chaw, kev kho mob qog noj ntshav tshiab thiab txawm tias kev kho cell.

Nov yog qee qhov tsis ntseeg siab uas peb cov tsiaj tam sim no tau siv los ua tsaug rau kev nce qib hauv kev kawm kho tsiaj.

Xov Xwm Tshiab Canine Cancer

Feem ntau ntawm cov tsiaj cov kab mob twb muaj kev txhaj tshuaj tiv thaiv uas tuaj yeem txo lossis tshem tawm kev pheej hmoo ua mob. Yog li cov kws tshawb nrhiav tau tam sim no tshawb nrhiav ntau tshaj cov kev xaiv los tiv thaiv thiab kho mob loj xws li mob qog noj ntshav.

Cov Lus Cim Theine canine melanoma yog cov tshuaj siv los pab kho tus mob qog nqaij hlav cancer. Nws tau hloov kho lub ntiaj teb veterinary science.

Dr. Carol Osborne, DVM, los ntawm Chagrin Falls Veterinary Center & Pet Clinic hais tias "The Oncept melanoma vaccine yog Merial txoj kev sim ua rau cov dev lub cev tiv thaiv kabmob tawm tsam tua kabmob thiab kho nws tus kheej." Dr. Osborne yog ib qhov kev sim tebchaws Asmeskas uas qhia txog kev tiv thaiv kabmob ntawm cov dev los xaiv cov kabmob uas tau siv tshuaj kho kom zoo dua. "Qhov no tawm tsam kev siv tshuaj kho mob, uas yog kev coj ua dhau los ntawm kev sim kho mob qog noj ntshav nrog tshuaj muaj kuab lom tab sis feem ntau tsis kho lossis tua tus kab mob."

Qhov tshuaj tiv thaiv canine melanoma yog tsim los ntawm DNA uas yog hloov nrog tib neeg cov protein hu ua tyrosinase (tyrosinase muaj nyob hauv cov hlwb hu ua melanocytes uas tsim cov xim uas hu ua melanin), Dr. Osborne piav qhia.

Dr. Osborne hais tias "Tib neeg tyrosinase zoo ib yam li canine tyrosinase." "Melanoma cov qog nqaij hlav cancer mob nrog tyrosinase, thiab txoj kev xav yog tias ob qho roj ntsha tiv thaiv thiab ua rau tus dev lub cev tshem tawm cov mob qog nqaij hlav."

Osinene qhia txog kev txhaj tshuaj tiv thaiv kab mob canine tau siv dav los ntawm cov kws kho mob qog noj ntshav hauv dev nrog theem 2 thiab 3 ntawm tus mob melanoma phem sim los pab tiv thaiv nws kom tsis txhob kis mus rau tus dev mob caj dab thiab lub ntsws, qhia txog Dr.

"Txij xyoo 2007, cov txiaj ntsig tau qhia tau tias cov dev uas tau txais kev phais thiab cov tshuaj tiv thaiv muaj sia nyob kwv yees li 12 lub hlis ntev dua li cov uas tau txais kev phais tab sis tsis tau txais tshuaj tiv thaiv," Dr. Osborne hais ntxiv.

Kev Siv Tshuaj Tiv Thaiv Mob Hlwb Mob Cancer rau Cov Tsiaj

Immunotherapy tau dhau los ua qhov kev kho kub rau kev mob qog noj ntshav hauv tsiaj, ua tsaug rau cov kev tshawb fawb tshiab zoo li cov kev tshawb fawb los ntawm Mason Immunotherapy cov kev tshawb fawb ntawm University of Pennsylvania School of Veterinary Medicine.

Osborne qhia txog kev tiv thaiv dev thiab miv muaj kev hloov pauv cov kab mob tshwj xeeb rau cov qog mis hlav tshwj xeeb. Qhov no yuam kom lub cev tiv thaiv kab mob tua cov mob hlwb thiab kho nws tus kheej.

Kev Kho Mob Gene

Cov kws tshawb fawb tseem tab tom saib mus rau hauv kev tso tshuaj DNA (rDNA) los pab kho mob qog nqaij hlav hauv dev.

Dr. Osborne hais tias "Recombinant DNA tau qhib qhov rooj rau kev kho noob." "Txawm hais tias muaj kev txhawj xeeb raug cai, kev kho cov noob yuav kho cov kab mob ntau yam los ntawm kev tso cai rau kws kho tsiaj hloov cov tsis txawv thiab / lossis ploj cov noob hauv cov tsiaj."

Kev tshawb fawb ua ntej muaj kev kho mob tshiab rau canine mammary cancer siv tus kab mob pob sawv hlwv, thiab kev tshawb fawb xyoo 2018 xaus tias "oncolytic virus tau txais hauv av raws li lwm txoj hauv kev los kho mob cancer hauv dev thiab tib neeg."

Thaum cov kev xaiv kho mob no tseem nyob rau theem pib ntawm kev loj hlob, lawv muaj lub ntiaj teb muaj peev xwm ntawm kev kho mob cancer hauv dev.

Hloov thiab Hloov Rau Tsiaj

Kev hloov kho cov qhov muag tau dhau los ua qhov chaw kho mob miv hauv cov dev, raws li Dr. Bruce Silverman, VMD, MBA, tus tswv ntawm Village West Veterinary. Dr. Silverman tseem hais ntxiv tias cov qog seev yuag kuj tseem ua kom muaj ntau hauv dev.

"Hloov khoom hauv lub cev, ntawm qhov tod tes, tseem yog qhov tsis tshua muaj thiab feem ntau ua rau hauv tsev kawm ntawv cov chaw," Dr. Silverman hais.

Cov feem ntau hloov khoom nruab nrog nyob rau lub sijhawm no yog hloov raum rau cov miv. Raws li lub Tsev Kawm Qib Siab Veterinary Tshuaj ntawm University of Georgia-ib qho ntawm ob peb lub hauv paus hauv lub tebchaws uas hloov miv lub raum hloov ntshav-tus neeg mob feem ntau yog tus miv uas muaj mob raum ntev, vim cov dev lub cev sib txawv thiab feem ntau yuav tsis kam lees raum tshiab.

Txoj haujlwm pabcuam hloov ntshav, uas muaj tsawg thiab tsis kim heev (lub raum hloov tau koj rov qab $ 15, 000), xav kom txhua tus neeg pub cov miv hloov los ntawm tsev neeg txais.

Hloov hlwb pob txha los kuj tseem muaj rau cov dev uas mob qog nqaij hlav, mob qog ntshav, mob ntshav ntau myeloma lossis dav dav tus mob mast cell, raws li Dr. Osborne. Dr. Osborne hais tias "North Carolina State Veterinary Hospital hauv Raleigh, North Carolina, thiab Veterinary Veterinary hauv Bellingham, Washington, hais cov txheej txheem," Dr.

Qhov xov xwm zoo yog cov dev uas hnyav dua 35 phaus yam tsis muaj kev ua rau lub cev ua haujlwm tau txaus siab rau 50 feem pua kho tus mob rau tus kab mob uas yav dhau los ua rau neeg tuag taus, hais tias Dr.

Tus kws kho mob Osborne hais tias, “Tus txheej txheem no koom tes heev thiab yuav tsum muaj ntau kauj ruam,” Dr. "Thawj cov dev tau siv tshuaj kho mob, uas yog siv los ua kom tiav kev kho mob kheesxaws, tom qab ntawd cov dev cov ntshav tau sau tawm, tom qab ntawd cov canines tau hla ob zaug ntawm lub cev tag nrho hluav taws xob."

Thaum kawg, cov qe ntshav uas tau muab los cog yuav hloov ntshav rov qab los rau hauv tus dev ua ntej nws npaj rau kev rov zoo, uas yuav tsum tau nyob hauv ob lub lis piam sib cais tag nrho, raws li Dr. Osborne.

Qia cell kho rau cov tsiaj

Qia cell kho siv feem ntau siv rau kev cuam tshuam tsis zoo hauv cov dev thiab miv.

Txawm hais tias qhov tshwm sim muaj qee qhov kev poob siab nyob rau lub sijhawm no vim tias nws yog qhov kev txhim kho tshiab, Dr. Osborne hais tias kev kho qia ntawm tes rau cov dev thiab miv yog qhov zoo heev los kho txhawm rau lub duav, lub luj tshib, stifles thiab lub xub pwg, feem ntau hauv cov dev.

Cov kws tshawb nrhiav tam sim no siv zog ua haujlwm los txuas ntxiv cov txiaj ntsig kho kom zoo ntawm kev kho lub qia ntawm tes rau cov dev thiab miv.

Dr. Osborne hais tias "Lub sijhawm tam sim no, kev txhim kho hauv kev sib koom ua ke, ntau yam txav chaw thiab lub neej zoo muaj qhov cuam tshuam ntev kawg rau qhov nruab nrab 6 lub hlis tom qab ua haujlwm," Dr. Osborne hais.