Lub Dreaded Mast Cell Tumor

2024 Tus sau: Daisy Haig | [email protected]. Kawg hloov kho: 2023-12-17 03:09

Ntawm tag nrho cov qog kuv kho, tej zaum qhov tsis tau paub tseeb tshaj plaws yuav yog dreaded canine mast cell qog. Kws phais mob kuv tau ua haujlwm nrog thaum lub sijhawm ua haujlwm xyaum haujlwm tau piav qhia nws txog kev mob qog noj ntshav hauv dev los ntawm kev qhia rau tus tswv, "Yog hais tias puas muaj tus qog yuav dag kuv thiab ua qhov nws xav tau, nws yog mast cell qog."

Kuv pom ntau qhov ntau, kuv pom tau tias kuv tus kheej rov hais cov lus txo hwj chim dua ib zaug thaum tham txog tus kab mob nyuaj no.

Feem ntau cov dev pib mob mast hlav hlav hauv lawv cov tawv nqaij lossis nqaij mos. Lawv kuj yuav ua tau hlav hlav sab hauv, tab sis qhov no tsis tshua muaj. Qhov tsis paub yog los thaum daim tawv nqaij hlav tawm sab hauv, lossis ib qho qog ntawm sab hauv mus rau ntawm daim tawv. Nws yuav luag tsis muaj peev xwm txiav txim siab tias "qaib lossis qe" nyob rau hauv cov teeb meem no.

Qee tus dev yuav raug kuaj nrog mast cell qog thaum ib lub qog uas tau nyob ntau xyoo thaum kawg kuaj ib hnub. Lwm tus dev yuav pib ua cov qog loj hlob tuaj uas tau hloov pauv sai sai hauv ob peb hnub luv mus rau lis piam. Qee qhov yuav muaj tsuas yog qog nyob tas lawv lub neej, thaum lwm tus yuav muaj lub kaum os lossis ntau dua kev txhim kho hauv lub sijhawm luv luv.

Kuv tseem tau pom cov dev uas pib mob qog tshiab txhua xyoo xws li moos ua haujlwm. Kuv yuav tau twv yuav raug kwv yees nws yog tej zaum feem ntau "mob cancer thib ob" Kuv kuaj hauv cov dev Kuv tabtom kho rau ib hom qog sib txawv.

Mast cells yog cov qe ntshav tiv thaiv kab mob uas ib txwm ua lub luag haujlwm hauv kev ua xua thiab cov kev sib kis. Lawv nyob rau hauv ntau cov ntaub so ntswg ntawm lub cev, thiab cov dev muaj qhov sib txuam ntawm cov hlwb no nyob hauv lawv cov tawv nqaij. Hlwb hlwb mast muaj cov granules, uas yog qhov tseeb ntim ntawm cov tshuaj. Thaum kos npe los ntawm kev tsis haum lossis lub cev tiv thaiv kab mob, mast cells yuav tso cov tshuaj tawm los ntawm cov txheej txheem hu ua degranulation. Cov tshuaj lom neeg tuaj yeem ua rau hloov chaw hauv zos, txoj cai ntawm thaj chaw uas lawv tso, thiab tseem tuaj yeem taug kev los ntawm cov ntshav ntws mus cuam tshuam rau cov kabmob thiab cov nqaij mos nyob deb, thiab txawm tias tag nrho lub cev, hauv qhov uas paub tias yog tshuaj tiv thaiv anaphylactic.

Peb tsis to taub tag nrho dab tsi ua rau mast cell qog yuav tsim, tab sis peb paub tias lawv muaj feem ntau yuav tshwm sim hauv qee qhov ntawm cov dev, suav nrog Boxers, Boston Terriers, Beagles, Pugs, Labrador retrievers, thiab Golden retrievers (rau npe ib ob peb). Qhov no qhia tau qhov yuav tshwm sim caj rau lawv keeb kwm. Mob voos ua ntev thiab mob ntev rau ntawm kev ua xua tej zaum yuav ua rau dev ua nqaij hlav.

Peb kuj paub tias nyob nruab nrab 20-30% ntawm mast cell hlav yuav muaj qhov hloov hauv ib qho kev tshwj xeeb hu ua c-pob. Qhov no yuav rov los dua ib tsab xov xwm yav tom ntej los tham txog kev kho mob rau mob mast cell, thiab yog lub hom phiaj rau chav kawm tshiab ntawm cov tshuaj kho mob hu ua tyrosine kinase inhibitors (saib tsab xov xwm ntawm Palladia).

Rau kev txiav mast cell hlav, ib qho kev twv ua ntej tshaj plaws ntawm yuav ua li cas "zoo" lossis "tsis zoo" nws yuav coj yog qee yam hu ua qib qog. Qeb tsuas yog txiav txim siab los ntawm kev siv tshuab me, uas txhais tau tias yog ib qho me me ntawm cov qog, lossis tag nrho cov qog, yuav tsum tau tshem tawm thiab ntsuas los ntawm tus kws kho mob.

Feem ntau muab cov qib rau cov mast cell hlav hauv cov dev yog qee yam hu ua Patnaik nplai, qhov twg cov qog yuav raug faib raws li qib 1, qib 2, lossis qeb 3. Feem ntau ntawm cov qog 1 yuav ua rau tsis zoo, thiab phais. kev zam tsis suav hais tias yog curative.

Ntawm sab nraud ntxiv ntawm cov yeeb yam yog qib 3 lub qog. Cov no yog cov xwm txheej tsis zoo, muaj feem ntau ntawm qhov yuav rov huam dua tom qab phais mob tas, thiab lub siab nrawm rau kis mus rau cov qog ntshav, hauv nruab nrog cev, thiab txawm tias tus mob pob txha.

Tej zaum qhov nyuaj tshaj plaws ntawm txhua qhov kom paub los kho yog cov qog qeb 2. Feem ntau ntawm cov qog qib 2 nws coj zoo ib yam li cov qog qib 1, tab sis ib qho me me yuav ua heev, thiab nws nyuaj rau kwv yees tias qhov twg yuav ua. Qee cov ntaub ntawv tuaj yeem khaws cia los ntawm cov ntaub ntawv me me qhia nws tus kheej, tab sis feem ntau peb tab tom ua peb qhov kev kwv yees zoo uas yuav ua dab tsi.

Vim tias kev tsis sib haum xeeb nyob ib puag ncig ntawm cov qog qeb 2, qhov kev paub muab qhab nia tshiab tau npaj txog li ob xyoos tsim los tso tag nrho cov qog ua ib los ntawm ob pawg. Siv cov qauv tshiab no, mast cell qog txiav txim siab tias yog qib siab lossis qib qis. Thaum kawg, zoo li cov av nkos yuav raug tshem tawm thiab cov qog tsuas hais tias "tsis zoo lossis qhov zoo."

Raws li muaj tseeb rau ntau yam, qhov tshiab tsis yog ib txwm zoo dua rau qee tus neeg, thiab tsis yog txhua tus kws kho mob tau los siv ob txoj kab xwm zoo. Kuv pom tias nws tau txais txiaj ntsig zoo rau tus kws kho mob tawm tswv yim kom suav nrog ob qho kev tsim tawm ntawm daim ntawv qhia me me, thiab ntau thiab ntau tus kws kho kab mob tseem tab tom ua yog li cov kab ke tshiab no zoo li tau qeeb qeeb.

Txawm hais tias ntau dua 80% ntawm cov tawv nqaij ua pob thiab tawv nqaij ua rau cov dev tawm tag, thiab txawm hais tias feem ntau canine cutaneous mast cell qog coj tus yam ntxwv tsis zoo, nws tseem tseem ceeb heev kom muaj ib qho tshiab lossis qub qog lossis cov tawv nqaij los ntawm kev soj ntsuam ntawm kws kho tsiaj (saib Qhov Kev Ntsuas Lej thiab Cov Pob Quav).

Tsis txhob xav tias qhov mob qog nqaij ntawd yog lub cev me, lossis tsuas yog "rog rog" los ntawm qhov xav. Tsawg tsawg kawg, ib rab koob txhaj tshuaj zoo yuav tsum tau ua kom txiav txim siab qhov ua rau lub qog. Siv nws los ntawm ib tug neeg uas tau dag ib zaug ntau dhau los ntawm tus kabmob no.

*

Lub asthiv tom ntej no kuv yuav tham txog cov kev kho mob rau mast hlav qog nqaij hlav hauv dev, suav nrog kev phais mob, kho hluav taws xob, thiab kho tshuaj.

Dr. Joanne Intile